Certificate Number:Certificate Number: Certificate expiration date:Certificate expiration date: Effective date:Effective date: 31-10-202231-10-2022 30-10-202530-10-2025 Expiry date of previous cycle:Expiry date of previous cycle: 30-10-202230-10-2022 31-10-201631-10-2016 ES133794ES133794 Scope of certification:Scope of certification: MANUFACTURING OF MASTERBATCHES, ADDITIVESMANUFACTURING OF MASTERBATCHES, ADDITIVES AND COMPOUNDS FOR PIGMENTING THERMOPLASTICAND COMPOUNDS FOR PIGMENTING THERMOPLASTIC MATERIALS USED IN FOOD INDUSTRYMATERIALS USED IN FOOD INDUSTRY ISO 22000:2018ISO 22000:2018 POLIGONO INDUSTRIAL EZCABARTE, C/H, Nº3 - 31194 - ORICAIN - NAVARRA - ESPAÑA AVIENT ESPAÑA, S.L.AVIENT ESPAÑA, S.L.

Ltd Business Registration Number: 91320505799067336K Registered/ Operation Address: 13 Plant, No.855, Zhujiang Road, Suzhou New District, Jiangsu Province, China by reason of its Environmental Management System has been awarded this certificate for compliance with the standard ISO 14001:2015 The Environmental Management System Applies in the following area: Production and Related Management Activities of Plastic Colorant & Additive (UV Blockers, Anti-Aging,Anti-Oxidation) Certified since: 2012年6月6日 Valid from: 2024年1月17日 Valid until: 2027年1月7日 the expiry date of last certification cycle: 2024年1月7日 the date ofrecertification audit: 2023年12月21日 to 2023年12月22日 After a surveillance cycle, the certificate is valid only when used together with an Acceptance Notice of Surveillance Audit issued by CQC.

L A B O R ATO RY E Q U I P M E N T M A N U FA C T U R E R P C R W E L L P L A T E S • Very high level of TiO2 to prevent “cross-talk” between the wells during the qPCR fluorescence testing procedure • Minimized background phosphorescence caused by agglomeration of TiO2 and/or oxidized (stressed) polystyrene • Preservation of polystyrene grade properties • Change control of formulation and manufacturing process • Robust product quality from batch to batch • Developed optimally dispersed, ready-to-use white formulation that maintains adequate signal transmission, as well as minimizing “cross-talk” and background phosphorescence • Optimized the use of general purpose polystyrene (GPPS) for a good balance between melt flow and other physical properties, such as stiffness • Provided comprehensive change control of raw materials and formulation, with a robust manufacturing process and quality control under a third party ISO 13485:2016 certified QMS Mevopur Healthcare Colorants and Formulations – pre-colored solution WHY AVIENT?

主要特性 在四个通过ISO 13485认证的医疗生产线生 产，拥有全球统一的配方，提供一致性和供 应链保障 变更控制记录的不限于CAS编号级别，降低变 更风险 不含动物源性物质和邻苯二甲酸盐 不同的琥珀色色调，可根据要求定制—偏红色 或偏黄色，和/或颜色浅或深 适用于液体形式 • • • • • 法规支持 经过预测试的原材料：- ISO 10993-1和USP第、 部分（VI级） - 欧洲药典，，美国药典， 元素分析符合ICH Q3D - USP 溶液性状、颜色标准 FDA发布的注册药品主文件（III类） 食品接触符合FDA/EU*要求 符合YBB00102002-2015 (口服液体药用聚酯 瓶）标准 • • • • 1.844.4AVIENT www.avient.com 适用医疗保健使用限制—见下文。

KEY CHARACTERISTICS • Meets critical need for thermal weldability and kink resistance • Minimizes extractables during processing • Provides excellent tensile strength • Complies with USP VI and ISO 10993-4, -5, -11 certifications • Suitable for gamma and autoclave sterilization methods • Bio-based grade option formulated with nearly 40% Gen 1 biomass content PRODUCT OVERVIEW 1.844.4AVIENT www.avient.com Copyright © 2023, Avient Corporation.

Polymer Diagnostics Inc. 33587 Walker Road Avon Lake, Ohio 44012 United States +1 800 438 2335 +1 440 930 1644 fax Polymer Diagnostics Inc. is a contract laboratory with accreditation to ISO/IEC 17025 by the American Association for Laboratory Accreditation (A2LA) for both chemical and mechanical capacities. 1 7 . 2 8 . 2 5 i n 8 . 5 i n 1 7 C M Y K HC_Industry bulletin_PDI_fi nal.indd REMAY 78810 TR: 16.5000" x 11.6875" and 17.000" x 11.000" Digital/IAM BL: 17.2500" x 11.9375" FINAL: 8.2500" x 11.6875" and 8.500" x 11.000" 11 .6 8 7 5 in 2 5 i n 11 .9 3 7 5 in 8 . 2 5 i n 8 . 5 i n 11 in i n Asset No. 78810 Polymer Diagnostics Inc. Polymer Diagnostics Inc. 33587 Walker Road Avon Lake, Ohio 44012 United States +1 800 438 2335 +1 440 930 1644 fax Polymer Diagnostics Inc. is a contract laboratory with accreditation to ISO/IEC 17025 by the American Association for Laboratory Accreditation (A2LA) for both chemical and mechanical capacities. 1 7 . 2 8 . 2 5 i n 8 . 5 i n 1 7 C M Y K HC_Industry bulletin_PDI_fi nal.indd REMAY 78810 TR: 16.5000" x 11.6875" and 17.000" x 11.000" Digital/IAM BL: 17.2500" x 11.9375" FINAL: 8.2500" x 11.6875" and 8.500" x 11.000" 11 .6 8 7 5 in 2 5 i n 11 .9 3 7 5 in 8 . 2 5 i n 8 . 5 i n 11 in i n Asset No. 78810

Composite panels for modular ISO shelters, transport containers and pallets TRANSPORTATION Rail car doors, floors and body panels, shipping containers, tractor trailer panels, large trucks, trailers, RVs, and mass transit vehicles MARINE Structural bulkheads, transoms, decks/soles, subflooring, and interior walls www.avient.com Copyright © 2020, Avient Corporation.

Using Avient’s Product Carbon Footprint Calculator, which has been third-party certified by TÜV Rhineland to ISO 14067 standard, the new Avient formulations enable a 50% carbon footprint reduction compared to the materials previously used.

KEY CHARACTERISTICS • Customized density offering a wide range of specific gravities (1.5–11 gm/cm3) • Formulated with partially bio-based resin from renewable plant sources • Broad modulus range, from very flexible to very rigid grades • Corrosion resistance that withstands oxidization for long-term use and benefit • Chemical resistance that can be adapted depending on base resin as required • Provides visual surface effects, aesthetics and cool touch • Design flexibility and processing ease • Food contact compliance available MARKETS AND APPLICATIONS Applications in packaging and consumer goods in which a more sustainable solution is preferred: • Cosmetic caps and closures • Perfume caps • Spirit bottle caps • Luxury boxes • Handles and knobs SUSTAINABILITY BENEFITS • Formulated with partially bio-based resin from renewable plant sources • Reduces waste and supports the circular economy • Reduces carbon footprint compared to fossil feedstock alternatives • Simplifies manufacturing and lowers cost versus metal PRODUCT BULLETIN CHARACTERISTICS UNITS Gravi-Tech BIO GT5200-5077 FD Natural Gravi-Tech BIO RS5200-5001 RS FD Natural Gravi-Tech BIO RS5200-5001 RS FD Natural X1 Gravi-Tech BIO GT5200-5003 FD Black Gravi-Tech BIO GT5200-5004 FD Black Gravi-Tech BIO GT5200-5002 FD Black Base Resin Bio-based PP Bio-based PP Bio-based PP Bio-based PP Bio-based PP Bio-based PP Recycled Content/Filler g/cm Mineral Mineral Mineral Metallic Metallic Metallic Density (ISO 1183) g/ccm 1.90 2.0 2.0 2.0 2.5 3.0 AVAILABLE GRADES Copyright © 2023, Avient Corporation.

GLOBAL REGULATORY COMPLIANCE Our regional tech centers around the world offer regulatory support and product stewardship expertise to help you qualify your products BIO-COMPATIBILITY APPLICATIONS Bio-compatible additives and colorants, tested under USP Class VI and ISO 10993, allow your materials to achieve required functional performance while meeting brand and color standards STERILIZATION REQUIREMENTS A standard color range and deliberate formulations provide stability under harsh sterilization methods AUTHENTICATION TECHNOLOGY Protect your brands with our Percept™ anti-counterfeit, security and tracking taggant technologies, or utilize radiopacifiers for placement protection LASER MARKING SOLUTIONS Optimized for color and contrast without diminishing physical property characteristics for branding, inventory management, data coding, or universal device identification PRODUCT & PROCESS OPTIMIZATION Maximize production throughput or eliminate waste with solutions including dimensional stabilization, cycle time reducers, chemical foaming agents, nucleation or hybrid technology ONCOLOR™ HC Colorants designed to be healthcare-friendly.