Whether your application demands can be supported by the NEUSoft Express color palette or require customization, all our NEUSoft TPUs are designed with patient safety and regulatory specifications in mind, complying with ISO 10993 and USP Class VI standards.

Zwolseweg 1, 2994 LB, Barendrecht, Netherlands - TEL: +31(0)102922689. www.dnv.com/assurance Certificate No: 2997-2006-AQ-RGC-RvA Initial certification date: 08 June, 2006 Valid: 11 April, 2022 – 11 April, 2025 This is to certify that the management system of Polyone - Suzhou, China EM Sector, 77 Shenggang Street, Suzhou Industrial Park, Suzhou, Jiangsu, China, 215024 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016/ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Plastic Compounding Material Certificate No: 2997-2006-AQ-RGC-RvA Place and date: Shanghai, 27 April, 2022 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid.

Certificate Number:Certificate Number: Certificate expiration date:Certificate expiration date: Effective date:Effective date: 31-10-202231-10-2022 30-10-202530-10-2025 Expiry date of previous cycle:Expiry date of previous cycle: 30-10-202230-10-2022 31-10-201631-10-2016 ES133794ES133794 Scope of certification:Scope of certification: MANUFACTURING OF MASTERBATCHES, ADDITIVESMANUFACTURING OF MASTERBATCHES, ADDITIVES AND COMPOUNDS FOR PIGMENTING THERMOPLASTICAND COMPOUNDS FOR PIGMENTING THERMOPLASTIC MATERIALS USED IN FOOD INDUSTRYMATERIALS USED IN FOOD INDUSTRY ISO 22000:2018ISO 22000:2018 POLIGONO INDUSTRIAL EZCABARTE, C/H, Nº3 - 31194 - ORICAIN - NAVARRA - ESPAÑA AVIENT ESPAÑA, S.L.AVIENT ESPAÑA, S.L.

Park, Pudong, Shanghai China, 201203 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016/ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Masterbatch Certificate No: 7071-1998-AQ-RGC-RvA Place and date: Shanghai, 19 March, 2021 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid.

Ltd Business Registration Number: 91320505799067336K Registered I Operation Address: 13 Plant, No.855, Zhujiang Road, Suzhou New District, Jiangsu Province, China by reason of its Quality Management System has been awarded this certificate for compliance with the standard ISO 9001:2015 The Quality Management System Applies in the following area: Production Activities of Plastic Colorant & Additive (UV Blockers, Anti-Oxidation, Anti-Aging) Certified since: 2009年1月8日 Valid from: 2024年1月16日 Valid until: 2027年1月4日 the expiry date of last certification cycle: 2024年1月4日 the date of recertification audit: 2023年12月21日 to 2023年12月22日 After a surveillance cycle, the certificate is valid only when used together with an Acceptance Notice of Surveillance Audit issued by CQC.

Ltd Business Registration Number: 91320505799067336K Registered/ Operation Address: 13 Plant, No.855, Zhujiang Road, Suzhou New District, Jiangsu Province, China by reason of its Environmental Management System has been awarded this certificate for compliance with the standard ISO 14001:2015 The Environmental Management System Applies in the following area: Production and Related Management Activities of Plastic Colorant & Additive (UV Blockers, Anti-Aging,Anti-Oxidation) Certified since: 2012年6月6日 Valid from: 2024年1月17日 Valid until: 2027年1月7日 the expiry date of last certification cycle: 2024年1月7日 the date ofrecertification audit: 2023年12月21日 to 2023年12月22日 After a surveillance cycle, the certificate is valid only when used together with an Acceptance Notice of Surveillance Audit issued by CQC.

L A B O R ATO RY E Q U I P M E N T M A N U FA C T U R E R P C R W E L L P L A T E S • Very high level of TiO2 to prevent “cross-talk” between the wells during the qPCR fluorescence testing procedure • Minimized background phosphorescence caused by agglomeration of TiO2 and/or oxidized (stressed) polystyrene • Preservation of polystyrene grade properties • Change control of formulation and manufacturing process • Robust product quality from batch to batch • Developed optimally dispersed, ready-to-use white formulation that maintains adequate signal transmission, as well as minimizing “cross-talk” and background phosphorescence • Optimized the use of general purpose polystyrene (GPPS) for a good balance between melt flow and other physical properties, such as stiffness • Provided comprehensive change control of raw materials and formulation, with a robust manufacturing process and quality control under a third party ISO 13485:2016 certified QMS Mevopur Healthcare Colorants and Formulations – pre-colored solution WHY AVIENT?

主要特性 在四个通过ISO 13485认证的医疗生产线生 产，拥有全球统一的配方，提供一致性和供 应链保障 变更控制记录的不限于CAS编号级别，降低变 更风险 不含动物源性物质和邻苯二甲酸盐 不同的琥珀色色调，可根据要求定制—偏红色 或偏黄色，和/或颜色浅或深 适用于液体形式 • • • • • 法规支持 经过预测试的原材料：- ISO 10993-1和USP第、 部分（VI级） - 欧洲药典，，美国药典， 元素分析符合ICH Q3D - USP 溶液性状、颜色标准 FDA发布的注册药品主文件（III类） 食品接触符合FDA/EU*要求 符合YBB00102002-2015 (口服液体药用聚酯 瓶）标准 • • • • 1.844.4AVIENT www.avient.com 适用医疗保健使用限制—见下文。

Certificate Avient Corporation A B S Q u al it y E va lu at io n s C er ti fic at io n E Certificate Of ConformanceCertificate Of Conformance This is to certify that the Quality Management System of: Avient CorporationAvient Corporation 33587 Walker Road, Building 428 Avon Lake OH 44012 United States has been assessed by ABS Quality Evaluations, Inc. and found to be in conformance with the requirements set forth by: ISO 9001:2015ISO 9001:2015 The Quality Management System is applicable to: Manufacture of plastic compounds, color and performance additives, engineered thermoplastics, vinyl resins, custom mixed plastic materials, custom and commodity colorants for plastics, polyurethane systems, and plasticizers with design and sampling support at Suwanee, GA, and purchasing, customer service, logistics, quality, design and sampling support at PolyOne Corporate Headquarters at Avon Lake, OH, and distribution of resins Certificate No: 31307 Certification Date: 12 OCT 1995 Effective Date: 11 JUL 2024 Expiration Date 07 OCT 2025 Revision Date: 17 JUL 2024 Dominic Townsend, PresidentDominic Townsend, President Copyright as of the Effective Date, ABS Quality Evaluations, Inc. Page 1 of 4 https://abs.ez2xs.com https://abs.ez2xs.com A B S Q u al it y E va lu at io n s C er ti fic at io n E ISO 9001:2015ISO 9001:2015 Certificate Of ConformanceCertificate Of Conformance ANNEXANNEX Certificate No.: 31307 Avient CorporationAvient Corporation At the below facilities FACILITYFACILITY NAMENAME FACILITY ACTIVITYFACILITY ACTIVITY ADDRESSADDRESS Avient - Birmingham Manufacturing The Manufacture of Pultruded and Filament wound components Pultrusion and CRTM 3943, Valley East Industrial Drive, Buildings 1,2,3,4 Birmingham - AL 35217 United States Avient - Birmingham Manufacturing The Manufacture of Pultruded and Filament wound components Pultrusion and Filament Wound Tubing 3968, Valley East Industrial Drive, Building 5 Birmingham - AL 35217 United States Avient - Birmingham Manufacturing The Manufacture of Pultruded and Filament wound components Pultrusion 3950, Valley East Industrial Drive, Building 6 Birmingham - AL 3517 United States Avient Corporation Management of QMS.

KEY CHARACTERISTICS • Meets critical need for thermal weldability and kink resistance • Minimizes extractables during processing • Provides excellent tensile strength • Complies with USP VI and ISO 10993-4, -5, -11 certifications • Suitable for gamma and autoclave sterilization methods • Bio-based grade option formulated with nearly 40% Gen 1 biomass content PRODUCT OVERVIEW 1.844.4AVIENT www.avient.com Copyright © 2023, Avient Corporation.